RecruitingPhase 3NCT07348640

Evaluation of the Efficacy and Safety of Magnetic Resonance Angiography (MRA) Using Gadopiclenol Compared to Gadoterate Meglumine in the Assessment of Steno-occlusive Disease in Adult Patients With Suspected Vascular Disease

A Prospective, Multi-National, Randomized, Double-Blind, Crossover Study to Evaluate the Efficacy and Safety of Gadopiclenol-enhanced MRA Compared to Gadoterate Meglumine-enhanced MRA in the Assessment of Steno-occlusive Disease in Adult Patients With Suspected Vascular Disease

Sponsor

Guerbet

Enrollment

315 participants

Start Date

Jul 28, 2026

Study Type

INTERVENTIONAL

Conditions

Steno-occlusive Disease

Summary

Compare the diagnostic performance of gadopiclenol against gadoterate meglumine in patients with vascular diseases of supra-aortic, peripheral, or abdominal / renal arteries using MRI

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Gadoterate meglumine (Dotarem) and a drug called gadopiclenol for people with steno-occlusive disease. The study is currently recruiting participants at 41 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGgadopiclenol

Gadopiclenol enhanced-Magnetic Resonance Angiography

DRUGGadoterate meglumine (Dotarem)

Gadoterate meglumine (Dotarem) enhanced-Magnetic Resonance Angiography

Locations(41)

University of California Los Angeles (UCLA)

Los Angeles, California, United States

UCHealth University of Colorado Hospital

Aurora, Colorado, United States

Northshore - Evanston Hospital

Evanston, Illinois, United States

Mayo Clinic

Rochester, Minnesota, United States

Houston Methodist Hospital

Houston, Texas, United States

University of Washington

Seattle, Washington, United States

Centre Hospitalier de l'Université de Montréal

Montreal, Quebec, Canada

Department of Radiology and Nuclear Medicine, University Hospital Brno

Brno, Czechia

Motol University Hospital

Prague, Czechia

CHU Hopitaux de Bordeaux - Groupe Hospitalier Pellegrin

Bordeaux, France

Hôpital Cardiovasculaire et Pneumologique

Bron, France

CHU Dijon Bourgogne

Dijon, France

CHU de Poitiers

Poitiers, France

Charité - Universitätsmedizin Berlin

Berlin, Germany

University Hospital Bonn

Bonn, Germany

UH Essen

Essen, Germany

University Hospital of Saarland

Homburg, Germany

Klinik fuer Diagnostische Radiologie and Neuroradiologie

Kiel, Germany

Department of Neuroradiology, UKSH Campus Lübeck

Lübeck, Germany

LMU University Hospital

München, Germany

Semmelweis University - Budapest

Budapest, Hungary

University of Debrecen - Debrecen

Debrecen, Hungary

University of Pecs Clinical Centre

Pécs, Hungary

Reparto di Neuroradiologia ASST Ospedale Papa Giovanni XXIII

Bergamo, Italy

Azienda Ospedaliera di Monserrato

Cagliari, Italy

ITAB -Institute of Advanced Biomedical Technologies University d'Annunzio of Chieti-Pescara

Chieti, Italy

Department of Diagnostic Imaging, Humanitas Research Hospital

Milan, Italy

Diagnostica per Immagini e Interventistica Ospedale Umberto I

Roma, Italy

Catholic University - Fondazione Policlinico Gemelli Advanced Radiology Center - Diagnostic Imaging and Oncologic Radiotherapy Dept. IRCCS Rome

Roma, Italy

Ospedale Ca' Foncello

Treviso, Italy

University Hospital No.1, Department of Radiology and Diagnostic Imagine

Bydgoszcz, Poland

Radiology Department, Uniwersyteckie Centrum Kliniczne w Gdansku

Gdansk, Poland

Medical University Lublin, Diagnostic Imaging Department

Lublin, Poland

Yonsei University Gangnam Severance Hospital

Seoul, Gangnam-gu, South Korea

Seoul National University Hospital

Seoul, Jongno-gu, South Korea

Seoul St. Mary's Hospital

Seoul, Seocho-gu, South Korea

Asan Medical Center

Seoul, Songpa-gu, South Korea

Ajou University Hospital

Gyeonggi-do, Suwon-si, South Korea

Diagnòstic per la Imatge

Barcelona, Spain

Hospital Clínico San Cecilio

Granada, Spain

Hospital Nuestra, Resonancia Magnetica NTRA

Madrid, Spain

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07348640