Phase II Study of Daily Adaptive Radiotherapy for Submandibular Gland-sparing in Head and Neck Cancer

This study is testing a technique called daily adaptive radiotherapy for head and neck cancer that aims to protect the submandibular glands (saliva glands under the jaw) from radiation damage. When these glands are damaged, it can cause permanent dry mouth. Adaptive radiotherapy adjusts the radiation plan daily based on changes in the patient's anatomy to better avoid healthy tissue. **You may be eligible if...** - You are 18 or older - You have confirmed squamous cell carcinoma of the head and neck - Both sides of your neck are included in the radiation treatment area - You are planned for curative radiotherapy (with or without chemotherapy) - You are able to lie comfortably for up to 1 hour in the radiation mask **You may NOT be eligible if...** - You have evidence of disease that has spread beyond the head and neck region - You are pregnant - You already have salivary gland problems before treatment that would reduce benefit from this approach Talk to your doctor to see if this trial is right for you.