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RecruitingNCT07349173

Peripersonal Space Representation in Upper Limb Segmental Exclusion

Study of the Representation of Action Peripersonal Space in Participants With Unilateral Segmental Exclusion of the Upper Limb Compared to Asymptomatic Subjects

Sponsor

Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est

Enrollment

60 participants

Start Date

Dec 4, 2025

Study Type

OBSERVATIONAL

Conditions

Segmental Exclusion SyndromeComplex Regional Pain Syndrome (CRPS)Upper Limb Neglect (Peripheral)

Summary

This study aims to evaluate the representation of action peripersonal space (PPS) in subjects suffering from unilateral segmental exclusion syndrome of the upper limb compared to healthy control subjects. Segmental exclusion is defined by non-use or under-use of a limb segment without central nervous system damage. The study hypothesizes that this syndrome leads to a modification (shrinkage) of the PPS representation. Participants will perform reachability judgments in a Virtual Reality (VR) environment.

Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Age ≥ 18 years.
  • Presenting unilateral exclusion symptom of the upper limb or part of the hand evolving for \> 3 months.
  • No contraindication to force work in daily activities.
  • Age ≥ 18 years.
  • No history of upper limb impairment with sequelae.

Exclusion Criteria12

  • Affiliated to a social security scheme.
  • Able to understand simple orders.
  • Visual impairments.
  • Central neurological pathology.
  • Unstabilized psychiatric pathology.
  • Communication or comprehension difficulties.
  • Under legal protection or unable to consent.
  • Pregnant or breastfeeding women.
  • Cervical pathology contraindicating VR headset use.
  • Epilepsy.
  • Upper limb pathology unrelated to exclusion.
  • Inability to stand for 40 minutes.
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Interventions

BEHAVIORALReachability Judgment Task in VR.

Participants wear an Oculus Quest 2 VR headset. They first perform a motor task to measure Real Reachable Distance (DMA-r). Then, they perform a perceptual task where they must judge, without moving, if a virtual object is reachable (DMA-p). The test evaluates different spatial planes (front, 45° right, 45° left) and heights (shoulder, navel).

Locations(1)

Institut Régional de Médecine Physique et de Réadaptation (IRR), Centre Louis Pierquin.

Nancy, France

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NCT07349173