A Phase IIa, Randomized, Double-Blind, Placebo-Controlled Trial of JKN2403 in COPD

This study is testing JKN2403, an experimental drug, for people with chronic obstructive pulmonary disease (COPD) — a lung condition that makes it hard to breathe. This is an early-phase trial comparing the drug to a placebo to see if it is safe and reduces COPD symptoms and flare-ups. **You may be eligible if:** - You are an adult with a confirmed COPD diagnosis - You have a history of cigarette smoking or other significant exposure known to cause COPD - You are on a stable, guideline-recommended COPD treatment - You have had COPD flare-ups or significant symptoms as defined by the study **You may NOT be eligible if:** - You have a history of asthma or another significant lung condition that could confuse the results - You have uncontrolled serious medical problems - You have immune system problems, active autoimmune disease, or a history of serious infections - You have had a recent COPD flare-up or active infection - You have had a recent cancer diagnosis (except certain low-risk, treated cancers) - You are pregnant or breastfeeding - You have received certain biologic drugs or vaccines recently Talk to your doctor to see if this trial is right for you.