Oral Mini Pulse Dexamethasone in Pediatric Vitiligo
The Efficacy and Safety of Oral Mini-pulse Dexamethasone in Active Non-segmental Vitiligo Within the Pediatric Age Group
Cairo University
22 participants
Feb 28, 2026
INTERVENTIONAL
Conditions
Summary
The goal of this clinical trial is to learn if oral mini pulse (OMP) dexamethasone works to treat active vitiligo in children and also learn about the safety of this drug within this age group the main questions it aims to answer are does OMP halt activity in active vitiligo and what medical problems patients might experience while using the drug with special attention to linear growth. Researchers will give OMP dexamethasone to participating patients to see if the drug works to treat active vitiligo and whether it has any effect on linear growth. Participants will take OMP dexamethasone two fixed days per week for a period of 3 months. before starting treatment, patients will do baseline evaluation and investigations then monthly evaluation to monitor progress, report any side effects at the end of treatment period response to drug, lab values and growth will be evaluated then final evaluation of growth will be done after stoppage of drug.
Eligibility
Inclusion Criteria4
- Active (VIDA +3 \& +4) non segmental vitiligo
- Age between 4-9yrs
- Males and Females
- Children with height measurements within the percentile range 5-95% of normal values for their age.
Exclusion Criteria5
- Segmental vitiligo.
- Stable vitiligo.
- History of endocrine disorders (growth hormone deficiency, thyroid disorders)
- Growth disorders (Turner's syndrome, Klinefelter's syndrome)
- Systemic diseases likely to affect growth (IBD, chronic renal failure)
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
patients will receive oral mini pulse dexamethasone 2 fixed consecutive days per week in a dose of 0.1mg/kg/day for a period of 3 months
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07353801