Study of QLS-111-FDC in Open-Angle Glaucoma or Ocular Hypertension

This study is testing QLS-111-FDC, a combination eye drop that pairs a new drug with a standard glaucoma medication (latanoprost), in people with open-angle glaucoma or elevated eye pressure (ocular hypertension). Researchers want to see if this combination lowers eye pressure more effectively. **You may be eligible if:** - You have mild to moderate open-angle glaucoma or elevated eye pressure in at least one eye - Your vision in each eye is at least 20/200 - You have an eye pressure of 19 mmHg or higher after a run-in period with latanoprost eye drops - You are willing to comply with the study schedule and treatments **You may NOT be eligible if:** - You have other significant eye diseases beyond glaucoma or high eye pressure - You have previously used a prostaglandin eye drop (like latanoprost) without a meaningful response - You have a history of angle-closure glaucoma, serious eye trauma, eye infection, inflammation, or prior eye surgery - You have an unusually thin or thick cornea - You have uncontrolled diabetes, kidney disease, high blood pressure, or low blood pressure - You are pregnant or nursing, or not using contraception Talk to your doctor to see if this trial is right for you.