RecruitingNot ApplicableNCT07354750

Effect of Parasternal Plane Block on Intraoperative Nociception

Effect of Parasternal Plane Block on Intraoperative Nociception in Pediatric Cardiac Surgery


Sponsor

Diskapi Yildirim Beyazit Education and Research Hospital

Enrollment

60 participants

Start Date

Jan 30, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

Effective pain control during pediatric cardiac surgery remains a major clinical challenge, particularly in procedures involving median sternotomy, which is associated with intense nociceptive stimulation. Inadequate intraoperative analgesia may lead to increased opioid requirements, hemodynamic instability, delayed extubation, and prolonged intensive care unit stay. Objective monitoring of nociception may provide valuable information beyond conventional hemodynamic parameters in this vulnerable population. This prospective randomized controlled study aims to evaluate the effect of ultrasound-guided parasternal plane block on intraoperative nociception in pediatric patients undergoing cardiac surgery with median sternotomy. Intraoperative nociception will be objectively assessed using the Pain Index Monitor (PAM), based on skin conductance measurements. The results of this study are expected to provide objective evidence regarding the efficacy of parasternal plane block in attenuating nociceptive responses during pediatric cardiac surgery and to support the integration of regional anesthesia techniques and objective nociception monitoring into perioperative pain management strategies for children.


Eligibility

Min Age: 6 MonthsMax Age: 7 Years

Inclusion Criteria6

  • Age between 6 months and 7 years
  • Scheduled for elective congenital cardiac surgery
  • Planned median sternotomy
  • American Society of Anesthesiologists (ASA) physical status II-III
  • Hemodynamically stable preoperative condition
  • Written informed consent obtained from a parent or legal guardian

Exclusion Criteria5

  • Emergency surgery or redo sternotomy
  • Age \<6 months or \>7 years
  • ASA physical status I or \>III
  • Severe neurological disorders preventing reliable application of behavioral pain scales
  • Failure to obtain written informed consent from a parent or legal guardian

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Interventions

PROCEDUREParasternal Plane Block

Ultrasound-guided bilateral parasternal plane block will be performed after induction of general anesthesia. The block will be performed after induction of anesthesia using 0.25% bupivacaine, with a total dose of 1.5 mg/kg, administered in equal volumes to both sides. The procedure will be carried out by experienced anesthesiologists under sterile conditions.

PROCEDUREGroup without peripheral nerve block

Patients assigned to this group will undergo the surgical procedure under standard general anesthesia without the use of any peripheral nerve block techniques.


Locations(1)

Ankara Etlik City Hospital

Ankara, Turkey (Türkiye)

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NCT07354750


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