RecruitingPhase 3NCT07355062

A Study to Evaluate the Efficacy and Safety of Veverimer for the Treatment of Metabolic Acidosis

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Veverimer in Adults With CKD and Metabolic Acidosis

Sponsor

Renibus Therapeutics, Inc.

Enrollment

150 participants

Start Date

Jan 13, 2026

Study Type

INTERVENTIONAL

Conditions

CKD Metabolic Acidosis

Summary

The purpose of this study is is to evaluate the efficacy and safety of veverimer in treating adults with moderate-to-severe chronic kidney disease (CKD) and metabolic acidosis.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Placebo and a drug called Veverimer for people with ckd and metabolic acidosis. The study is currently recruiting participants at 22 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGVeverimer

Group 1: 9 g veverimer BID

DRUGPlacebo

Group 2: 9 g PBO BID

Locations(24)

Study Site

Chula Vista, California, United States

Study Site

Los Angeles, California, United States

Study Site

Sacramento, California, United States

Study Site

San Diego, California, United States

Study Site

Aurora, Colorado, United States

Study Site

Newark, Delaware, United States

Study Site

Edgewater, Florida, United States

Study Site

Margate, Florida, United States

Study Site

Miami Springs, Florida, United States

Study Site

Orlando, Florida, United States

Study Site

Augusta, Georgia, United States

Study Site

Boise, Idaho, United States

Study Site

Chubbuck, Idaho, United States

Study Site

Idaho Falls, Idaho, United States

Study Site

Chicago, Illinois, United States

Study Site

Indianapolis, Indiana, United States

Study Site

Louisville, Kentucky, United States

Study Site

Kansas City, Missouri, United States

Study Site

Fresh Meadows, New York, United States

Study Site

New York, New York, United States

Study Site

Winston-Salem, North Carolina, United States

Study Site

Fort Worth, Texas, United States

Study Site

Houston, Texas, United States

Study Site

San Antonio, Texas, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

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NCT07355062

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