RecruitingNCT07359586

Laryngopharyngeal Injury After Endotracheal Intubation Under General Anesthesia

Incidence,Perioperative Risk Factors and Prognosis Associated With Laryngopharyngea Injury After Endotracheal Intubation Under General Anesthesia:A Retrospective Study


Sponsor

Zhejiang University

Enrollment

1,200 participants

Start Date

Nov 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This study retrospectively analyzed patients who underwent tracheal intubation under general anesthesia at the First Affiliated Hospital of Zhejiang University School of Medicine between October 1, 2015, and September 30, 2025, with a focus on issues related to postoperativelaryngopharyngeal complaints. Patients requiring otolaryngological consultation due to postoperative laryngopharyngeal complaints were identified via the case consultation system. Relevant patient data were collected through the Medison Anesthesia Information Management System and electronic medical record system, and telephone follow-up was conducted to assess patient prognosis. The primary outcome measures were the risk factors of postoperative hoarseness, while the secondary outcome measures included the incidence of postoperative hoarseness, the severity of vocal fold injury and its related risk factors. Additionally, the prognosis of patients and its related risk factors were evaluated. This study aims to reduce the incidence of perioperative laryngopharyngeal injury and provide a reference for the optimization of perioperative anesthetic regimens.


Eligibility

Plain Language Summary

Simplified for easier understanding

This study examines the types and severity of throat and voice box injuries that can occur after a breathing tube is placed during general anesthesia for surgery, helping doctors better understand and prevent these complications. **You may be eligible if...** - You had general anesthesia with a breathing tube (endotracheal intubation) at the First Affiliated Hospital of Zhejiang University between October 2015 and September 2025 - After surgery, you had throat or voice problems (such as hoarseness, sore throat, coughing, or difficulty swallowing) - Your surgery was not on the ears, nose, or throat **You may NOT be eligible if...** - You already had known problems with your throat or voice box before surgery (such as polyps, tumors, or vocal cord paralysis) - You had a tracheostomy (a breathing hole in the neck) before or after surgery - Your medical records are incomplete - It was unclear which surgery caused your throat symptoms if you had multiple surgeries Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(2)

he First Affiliated Hospital, Zhejiang University School of Medicine

Hangzhou, Zhejiang, China

The First Affiliated Hospital, Zhejiang University School of Medicine

Hangzhou, Zhejiang, China

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NCT07359586


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