RecruitingNot ApplicableNCT07359664

OCTA in Cardiovascular Disease and Healthy Controls

Optical Coherence Tomography Angiography (OCTA) for the Assessment of Retinal Capillary Density in Patients With Cardiovascular Disease and a Healthy Control Group


Sponsor

University of Erlangen-Nürnberg Medical School

Enrollment

64 participants

Start Date

Dec 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This prospective clinical study will involve the non-invasive assessment of retinal vessels using OCTA (Cirrus OCT 6000 AngioPlex) and scanning laser Doppler flowmetry (SLDF) in patients with cardiovascular disease and healthy individuals. The study will be conducted at the Clinical Research Centre (CRC), Department of Nephrology and Hypertension at the University of Erlangen-Nuremberg.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study uses a specialized eye imaging technique (optical coherence tomography angiography, or OCTA) to look at tiny blood vessels in the retina of people with cardiovascular diseases, to see if eye changes can reveal information about heart and vascular health. **You may be eligible if...** - You have one or more cardiovascular conditions such as high blood pressure, type 2 diabetes, chronic kidney disease, or heart failure, OR - You are a healthy adult with a normal BMI (18–29.9), a non-smoker, and in good general health (to serve as a comparison group) **You may NOT be eligible if...** - You have an active eye disease that affects the retina (such as glaucoma, cataracts affecting the view, or retinal swelling) - For healthy volunteers: you have a history of heart, kidney, liver, neurological, or metabolic disease; your blood pressure is 140/90 or higher; you take heart or blood pressure medications Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTRetinal vascular assessment using OCTA and SLDF

Assessment of retinal capillary density using OCTA and SLDF


Locations(1)

University of Erlangen Nuremberg

Erlangen, Bavaria, Germany

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NCT07359664


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