RecruitingNot ApplicableNCT07359755

Vaginal Mesh Surgery Versus Robotic-assisted Abdominal Mesh Surgery in the Treatment of Apical Prolapse - Prospective Randomized Non-inferiority Study

A Comparative Analysis of Vaginal Mesh Surgery Versus Robotic-assisted Abdominal Mesh Surgery in the Treatment of Apical Genital Prolapse: a Prospective Randomized Non-inferiority Study.


Sponsor

University of Sao Paulo General Hospital

Enrollment

86 participants

Start Date

Sep 15, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this study is to compare vaginal mesh surgery with abdominal robotic-assisted mesh surgery for the treatment of genital prolapse in women. The main questions it seeks to answer are: * Is the objective cure rate for vaginal mesh surgery non-inferior to that of the abdominal approach? * Is the use of vaginal mesh as safe as abdominal mesh?


Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria1

  • The study will include patients diagnosed with apical compartment genital prolapse of stage II or higher, who have an indication for surgical correction.

Exclusion Criteria3

  • individuals with a prior history of pelvic radiotherapy;
  • patients with congenital or acquired anomalies of the urogenital or gastrointestinal systems;
  • and those with medical conditions that constitute a contraindication to elective surgical intervention.

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Interventions

PROCEDUREVaginal mesh surgery for apical prolapse

Cirurgia com tela vaginal para prolapso apical.

PROCEDURERobotic-assisted abdominal mesh surgery with Upsylon device (Boston Scientific - USA) for vaginal apical prolapse

Cirurgia robótica assistida por tela abdominal com dispositivo Upsylon (Boston Scientific - EUA) para prolapso apical vaginal.


Locations(1)

Hospital das Clinicas da Faculdade de Medicina de Sao Paulo

São Paulo, São Paulo, Brazil

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NCT07359755


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