RecruitingNot ApplicableNCT07360249

Glucose-fructose Ratio Pilot

PILOT TEST OF GLUCOSE-FRUCTOSE RATIOS ON EXOGENOUS CARBOHYDRATE OXIDATION RATES DURING EXERCISE


Sponsor

University of Bath

Enrollment

10 participants

Start Date

Jan 14, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The aim of this pilot study is to estimate the effect size of changing the glucose-fructose ratio from 1:0.5 to 1:1 on exogenous carbohydrate oxidation rates during exercise, which can be used to power a future definitive study.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Age: 18 years and above;
  • Performing endurance training for at least 5 hours per week
  • Capable of three hours of continuous exercise

Exclusion Criteria4

  • Glucose or lipid lowering, or weight loss medication
  • Diagnosis of cardiovascular disease, renal failure, liver disease or type 2 diabetes
  • Contraindications to exercise
  • Pregnant or lactating

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Interventions

OTHERGlucose and fructose (one-to-one)

Glucose and fructose ingested in solution in a one-to-one ratio (135 grams per hour for 3 hours during exercise)

OTHERGlucose and fructose (two-to-one)

Glucose and fructose ingested in solution in a two-to-one ratio (135 grams per hour for 3 hours during exercise)


Locations(1)

University of Bath

Bath, Bath, United Kingdom

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NCT07360249


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