RecruitingNot ApplicableNCT07361952

Oral Versus Intravenous Fluid Therapy in the Emergency Department


Sponsor

Esbjerg Hospital - University Hospital of Southern Denmark

Enrollment

250 participants

Start Date

Oct 3, 2025

Study Type

INTERVENTIONAL

Summary

The goal of this randomized clinical feasibility trial is to determine whether oral fluid therapy can achieve prescribed fluid volumes as effectively as intravenous fluid therapy in adult patients admitted to the emergency department who require fluid treatment. The main questions it aims to answer are: Are patients receiving oral fluids equally likely to achieve the prescribed fluid volume compared with patients receiving intravenous fluids? Is it feasible to conduct a randomized trial of oral versus intravenous fluid therapy in the emergency department, based on recruitment rate and protocol adherence? Researchers will compare oral tap water administration with standard intravenous crystalloid therapy to assess whether oral fluids are non-inferior in achieving prescribed fluid volumes and to evaluate feasibility outcomes. Participants will: Be randomized to receive either oral tap water or intravenous crystalloid fluids during their stay in the emergency department Receive a fluid volume and administration rate determined by the treating physician Be monitored according to standard clinical practice during the emergency department stay Have fluid intake, vital signs, and clinical outcomes recorded, with follow-up through routine health records up to 30 days after inclusion


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether drinking water by mouth can be just as effective as receiving intravenous (IV) fluids in adult patients who come to the emergency department and need fluid treatment. Many patients who need fluids are physically capable of drinking, and oral fluids could be simpler, safer, and more comfortable than an IV drip. Adults aged 18 and older who have been prescribed at least 1000 mL of IV fluids by an emergency physician may be eligible, while people who are unconscious, pregnant, have a bowel obstruction, or require intensive care are excluded. Participation involves being randomly assigned to drink tap water or receive standard IV fluids, with clinical monitoring and follow-up through medical records for up to 30 days. This summary was generated with AI assistance to help patients understand the study in plain language.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHEROral fluids

Any fluid volume prescribed by the physician during the ED stay is administered orally.

OTHERIntravenous fluids

Any fluid volume prescribed by the physician during the ED stay is administered intravenously.


Locations(3)

Emergency Department, South Jutland Hospital

Aabenraa, Denmark

Emergency Department, Esbjerg Hospital

Esbjerg, Denmark

Odense University Hospital

Odense, Denmark

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NCT07361952