RecruitingNot ApplicableNCT07363343

Nifedipine and Enalapril vs Nifedipine and Labetalol for the Treatment of Postpartum Hypertension Study

Nifedipine and Enalapril vs Nifedipine and Labetalol for the Treatment of Postpartum Hypertension Study (NEPHRON)

Sponsor

The Cleveland Clinic

Enrollment

200 participants

Start Date

Mar 10, 2026

Study Type

INTERVENTIONAL

Conditions

Hypertension Postpartum Preeclampsia

Summary

To determine if nifedipine and enalapril will have better blood pressure control in the postpartum setting compared to nifedipine and labetalol.

Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Nifedipine and Enalapril and a drug called Nifedipine and Labetalol for people with hypertension and postpartum preeclampsia. The study is currently recruiting participants at 1 location. People eligible for this study include women aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGNifedipine and Enalapril

Nifedipine 60mg by mouth every twelve hours plus Enalapril 5mg by mouth every twelve hours

DRUGNifedipine and Labetalol

Nifedipine 60mg by mouth every twelve hours plus Labetalol 200mg by mouth every twelve hours

Locations(1)

Cleveland Clinic

Cleveland, Ohio, United States

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NCT07363343

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