Immune Profile and Respiratory Parameters in Down Syndrome Children With Acute Pneumonia: Pre-Intervention Analysis
Relationship Between Immune Profile and Respiratory Parameters in Down Syndrome Children With Acute Pneumonia: Pre-Intervention Analysis
Badr University
40 participants
Jul 1, 2025
OBSERVATIONAL
Conditions
Summary
Baseline serum IgG, IgA, IgM (nephelometry), total WBC count (automated analyzer), RR (manual count), and SaO2 (pulse oximetry) were measured. Pearson or Spearman correlations were used to assess relationships between immune and respiratory variables, and with age
Eligibility
Inclusion Criteria2
- Down Syndrome with acute bronchopneumonia
- sufficient cognitive ability
Exclusion Criteria2
- severe congenital heart defects
- primary immunodeficiencies
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Interventions
Baseline serum IgG, IgA, IgM (nephelometry), total WBC count (automated analyzer), RR (manual count), and SaO2 (pulse oximetry) were measured. Pearson or Spearman correlations were used to assess relationships between immune and respiratory variables, and with age.
Locations(2)
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NCT07366593