RecruitingNCT07366684

Clinical Characteristics, Frailty, and Prognostic Predictors in Patients Aged 75 and Older With Acute Coronary Syndrome

Investigation of Clinical Characteristics, Frailty, and Predictors of In-Hospital and Six-Month Prognosis in Hospitalized Patients Aged 75 Years and Older With Acute Coronary Syndrome


Sponsor

Clinical Center Niš

Enrollment

550 participants

Start Date

May 13, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

This study will evaluate clinical characteristics, frailty, and predictors of prognosis in patients aged 75 years and older who are hospitalized with acute coronary syndrome (ACS). The research includes both a retrospective and a prospective cohort. The aim is to determine whether frailty scores, combined with clinical and laboratory parameters available at admission, can improve risk prediction for complications and mortality compared with standard risk scores (TIMI, GRACE, Syntax). The study will also compare outcomes between patients treated with percutaneous coronary intervention (PCI) and those treated conservatively with medications. Patients will be followed during hospitalization and for six months after discharge. The results are expected to contribute to more personalized treatment strategies for elderly patients with ACS.


Eligibility

Min Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Conservative Medical Therapy and a procedure called Percutaneous Coronary Intervention (PCI) for people with non st elevation myocardial infarction (nstemi), st elevation (stemi) myocardial infarction, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 75 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREPercutaneous Coronary Intervention (PCI)

Patients receiving PCI as part of routine clinical care

OTHERConservative Medical Therapy

Patients treated conservatively with guideline-directed medical therapy as part of routine care


Locations(1)

Clinical Center Niš

Niš, Serbia

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NCT07366684


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