Comparison of the Analgesic Efficacy of Erector Spinae Plane Block in Breast-Conserving Surgery Versus Serratus Anterior Block Combined With Additional Pecto-Intercostal II Block
Comparison of Analgesic Efficacy and Opioid Consumption of Erector Spinae Plane Block Versus Serratus Anterior Block With Additional Pecto-Intercostal II Block in Breast-Conserving Surgery
Kayseri City Hospital
70 participants
Apr 10, 2026
INTERVENTIONAL
Conditions
Summary
This prospective randomized study will compare the effects of Erector Spinae Plane Block (ESPB) and Serratus Anterior Plane Block combined with Pectoral Nerve Block Type II (SAPB + PECS II) on intraoperative analgesia and postoperative opioid consumption in patients undergoing breast cancer surgery. Seventy patients (ASA I-III, aged 18-75 years) will be randomized into two groups using the sealed envelope method. Ultrasound-guided blocks will be performed preoperatively by the same anesthesiologist, with Group 1 receiving ESPB and Group 2 receiving a combined SAPB + PECS II technique performed through a single skin puncture (single needle entry site) with sequential injections into the two target fascial planes. All patients will undergo surgery under general anesthesia and receive postoperative analgesia via morphine patient-controlled analgesia. Pain scores and total opioid consumption will be statistically analyzed, with p \< 0.05 considered significant.
Eligibility
Inclusion Criteria5
- Age between 18 and 75 years
- ASA physical status I-III
- No history of bleeding or coagulation disorders
- Absence of neuropathy
- Preoperative breast region NRS score < 4
Exclusion Criteria3
- systemic or regional infection
- known allergy to local anesthetics
- Unwillingness to participate in the study
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
Investigators will perform both blocks with a single injection.
Investigators will perform the block before the patient receives general anesthesia and investigators will check it with the pinprick test.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07368413