Cerclage Plus Progesterone vs Progesterone Alone in Twin Short Cervix

Exclusion Criteria11

• A potential paticipant who meets any of the following criteria will be excluded from participation in this trial:
• Women with twin pregnancy in which one or both fetuses are diagnosed with a major structural or congenital abnormality that is likely to influence the composite adverse neonatal outcome.
• Women with a monochorionic monoamniotic twin pregnancy
• A monochorionic twin pregnancy with twin-to-twin transfusion syndrome before or at the time of inclusion.
• Patients have indications for vaginal cerclage: Recurrent late miscarriage (from 14 weeks) or preterm birth occurring two or more times.
• Women with dilatation of the cervix diagnosed by ultrasound or physical exam
• Women with overt symptoms of preterm labor at the time of measurement of the short cervix (regular contractions, PPROM, recurrent blood loss).
• Women with the presence of fever ≥ 38 degrees Celsius.
• Women with a placenta previa, vasa previa.
• Uterine malformations: unicornuate uterus, bicornuate uterus, uterine septum, fibroid…
• Severe maternal conditions (heart failure, chronic kidney disease, systemic lupus erythematosus …)