RecruitingNCT07377747

Prospective Study Evaluating the Treatment Outcomes for Localised Recurrent, Resectable Retroperitoneal Liposarcoma


Sponsor

Australia and New Zealand Sarcoma Association

Enrollment

100 participants

Start Date

Sep 5, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The aim of the study is to collect prospective data on the treatment outcomes in patients with first localized, resectable recurrent retroperitoneal well-differentiated and/or dedifferentiated liposarcoma undergoing curative intent treatment. Patients enrolled in this study will form a validation cohort of the TARPSWG recurrent RPS nomogram. The treatment decision (surgery alone, or preoperative RT +/- chemotherapy followed by surgery) is per the institutional multidisciplinary team recommendation.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study evaluates treatment outcomes for patients with relapsed retroperitoneal liposarcoma — a fatty tissue cancer in the back of the abdomen — that has come back after initial surgery and can be removed again. The study examines surgery combined with radiation therapy. **You may be eligible if...** - You are 18 or older with a confirmed first recurrence of well-differentiated or dedifferentiated liposarcoma in the retroperitoneal space (behind the abdomen) - Your original tumor was fully removed (R0 or R1 resection) and no distant spread has been found on recent scans - Your tumor can be surgically removed again - You have never received radiation to this area before - Your general health is sufficient for surgery and radiation **You may NOT be eligible if...** - Your disease cannot be fully removed or is likely to require incomplete resection - Your cancer has spread to distant organs - You are pregnant - You have another active cancer Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(9)

Emory Winship Cancer Institute

Atlanta, Georgia, United States

OSU James Hospital

Columbus, Ohio, United States

MD Anderson Cancer Center

Houston, Texas, United States

Chris O'Brien Lifehouse

Camperdown, New South Wales, Australia

Prince of Wales Hospital

Randwick, New South Wales, Australia

Peter MacCallum Cancer Centre

Melbourne, Victoria, Australia

UZ Leuven

Leuven, Flemish Brabant, Belgium

A.C.Camargo Cancer Center - Fundacao Antonio Prudente

Liberdade, São Paulo, Brazil

The Netherlands Cancer Institute

Amsterdam, North Holland, Netherlands

View Full Details on ClinicalTrials.gov

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NCT07377747


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