RecruitingNot ApplicableNCT07378813

Low Versus High Load Training and Parkinson's Disease

Comparison of Changes in Neuromuscular and Functional Performance Due to Resistance Training With Low-Load or High-Load in Persons With Parkinson's Disease.


Sponsor

University of Miami

Enrollment

60 participants

Start Date

Jan 30, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This study will compare the effects of high-load resistance training to low-load resistance training, on measures of muscle strength and power and tests of daily performance in older adults with Parkinson's disease.


Eligibility

Min Age: 50 YearsMax Age: 85 Years

Plain Language Summary

Simplified for easier understanding

This study compares the effects of low-load versus high-load resistance training on strength, function, and quality of life in people with Parkinson's disease, to determine which approach is more beneficial. **You may be eligible if...** - You have Parkinson's disease at Hoehn & Yahr stages 1–3 (mild to moderate) - You can walk at least 50 meters without assistance - You can understand and communicate in English - You scored above 18 on a cognitive assessment (MoCA test) **You may NOT be eligible if...** - You have uncontrolled heart disease or another neuromuscular condition that prevents exercise - You have rheumatoid arthritis or another serious inflammatory condition - You have an unresolved injury or surgery to your arms or legs that prevents weight training Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALLow-Load Resistance Training

Participants will receive a total of twenty-four 45-minutes in-person training sessions, twice per week using three sets of eight repetitions per set. During training participants will be allowed 2-minute rests between sets. Exercises will include four upper-body exercises and two lower-body exercises.

BEHAVIORALHigh-Load Resistance Training

Participants will receive a total of twenty-four 45-minutes in-person training sessions, twice per week using four sets of eight repetitions per set. During training participants will be allowed 2-minute rests between sets. Exercises will include four upper-body exercises and two lower-body exercises.


Locations(1)

Laboratory of Neruomuscular Research and Active Aging

Coral Gables, Florida, United States

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NCT07378813


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