Low Versus High Load Training and Parkinson's Disease
Comparison of Changes in Neuromuscular and Functional Performance Due to Resistance Training With Low-Load or High-Load in Persons With Parkinson's Disease.
University of Miami
60 participants
Jan 30, 2026
INTERVENTIONAL
Conditions
Summary
This study will compare the effects of high-load resistance training to low-load resistance training, on measures of muscle strength and power and tests of daily performance in older adults with Parkinson's disease.
Eligibility
Inclusion Criteria4
- Parkinson's Disease Hoehn \& Yahr Stages 1-3
- Able to walk 50m unassisted
- Able to understand and communicate in English
- A Montreal Cognitive Assessment (MoCA) score above 18
Exclusion Criteria3
- Uncontrolled cardiovascular or other neuromuscular disease that prevent participation in a training program
- Any systemic inflammatory or autoimmune conditions such as rheumatoid arthritis, or other serious concomitant medical illness
- Unresolved injury or surgery to the upper or lower limbs that prevents weight training.
Interventions
Participants will receive a total of twenty-four 45-minutes in-person training sessions, twice per week using three sets of eight repetitions per set. During training participants will be allowed 2-minute rests between sets. Exercises will include four upper-body exercises and two lower-body exercises.
Participants will receive a total of twenty-four 45-minutes in-person training sessions, twice per week using four sets of eight repetitions per set. During training participants will be allowed 2-minute rests between sets. Exercises will include four upper-body exercises and two lower-body exercises.
Locations(1)
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NCT07378813