RecruitingNot ApplicableNCT07141849

Periodization and Parkinson's Disease

Comparison of Changes in Neuromuscular and Functional Performance Due to Block Periodization or Traditional Power Training in Persons With Parkinson's Disease.


Sponsor

University of Miami

Enrollment

60 participants

Start Date

Aug 29, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study will compare the effects of high-speed power resistance training to periodized training, which includes cycle of hypertrophy, strength and power, on measures of muscle strength and power and tests of daily performance in older adults with Parkinson's disease.


Eligibility

Min Age: 50 YearsMax Age: 85 Years

Inclusion Criteria3

  • Parkinson's Disease Hoehn \& Yahr Stages 1-3
  • Able to walk 50m unassisted
  • Able to understand and communicate in English

Exclusion Criteria3

  • Uncontrolled cardiovascular or other neuromuscular disease that prevent participation in a training program
  • Any systemic inflammatory or autoimmune conditions such as rheumatoid arthritis, or other serious concomitant medical illness
  • Unresolved injury or surgery to the upper or lower limbs that prevents weight training.

Interventions

BEHAVIORALPower Resistance Training

Participants will receive a total of twenty-four 45-minutes in-person training sessions, twice per week using three sets of eight repetitions per set. During training participants will be allowed 1-minute rests between sets. Exercises will include six upper-body exercises and five lower-body exercises.

BEHAVIORALPeriodized Resistance Training

Participants will receive three weeks of hypertrophy training to increase muscle size followed by six weeks of strength training, and then three weeks of power training twice per week for a total of twenty-four 45-minutes in-person training sessions. During training participants will be allowed 1-minute rests between sets. Exercises will include six upper-body exercises and five lower-body exercises.


Locations(1)

Laboratory of Neuromuscular Research and Active Aging

Coral Gables, Florida, United States

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NCT07141849


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