RecruitingNot ApplicableNCT07380009

Acceptability and Adherence to Different Dosing Regimens of the Multistrain Probiotic Vivomixx® 460 Neo 9 in Adults Receiving Antibiotic Therapy.

Acceptability and Adherence to Different Dosing Regimens of the Multistrain Probiotic Vivomixx® 460 Neo 9 in Adults Receiving Antibiotic Therapy: a Randomized, Open-label Clinical Trial.


Sponsor

University of Thessaly

Enrollment

40 participants

Start Date

Dec 12, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This open-label interventional study aims to evaluate the acceptability and adherence of adult participants to the multistrain probiotic Vivomixx® 460 Neo 9 when administered concurrently with antibiotic therapy. Participants are randomized to receive one of two dosing regimens: a low daily dose or a high daily dose. The study will assess the effects of these regimens on the prevention of antibiotic-associated diarrhea (AAD), gastrointestinal symptoms, and patient adherence and acceptability. The results are intended to provide evidence to optimize the clinical use of probiotics alongside antibiotics.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying One sachet of the probiotic daily and Two sachets of the probiotic daily for people with antibiotic therapy. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTOne sachet of the probiotic daily

Twenty participants will receive one sachet of the probiotic daily.

DIETARY_SUPPLEMENTTwo sachets of the probiotic daily

Twenty participants will receive two sachets of the probiotic daily.


Locations(1)

School of Physical Education, Sport Science and Dietetics

Trikala, Greece

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NCT07380009