RecruitingNCT07380711

Long-term Real-world Study of Dupilumab in COPD : Patient Characteristics, Safety and Patient-reported Outcomes

Prospective and Retrospective Observational Real-world Study to Characterize Patients With COPD on Dupilumab Long-term Treatment, and Assess Safety and Patient Reported Outcomes

Sponsor

Sanofi

Enrollment

500 participants

Start Date

Jan 28, 2026

Study Type

OBSERVATIONAL

Conditions

Chronic Obstructive Pulmonary Disease (COPD)

Summary

The OBS19236 is a retrospective and prospective, non-interventional observational study in COPD patients treated with dupilumab as part of routine clinical care. It will follow-up about 350 to 500 participants over 36 months in up to 50 sites in France.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This long-term real-world study collects information about patient characteristics, safety outcomes, and quality of life in adults with severe, uncontrolled COPD (a lung disease) who are starting dupilumab — a newer biologic injection therapy — as part of their standard care. **You may be eligible if...** - You are an adult with COPD that is not adequately controlled despite maximum inhaler therapy - Your blood eosinophil count is at least 300 cells per microliter (a marker showing your COPD may respond to dupilumab) - Your doctor has already decided to prescribe dupilumab for your COPD, independent of this study - You are willing to allow your anonymized clinical data to be used for research **You may NOT be eligible if...** - You are not eligible for dupilumab according to the medication's approved prescribing guidelines - You are currently in another interventional clinical trial - You have a condition that would make it difficult to complete questionnaires or participate fully Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(22)

Investigational Site Number : 2500021

Aix-en-Provence, France

Investigational Site Number : 2500043

Blois, France

Investigational Site Number : 2500044

Brest, France

Investigational Site Number : 2500009

Colmar, France

Investigational Site Number : 2500031

Contamine-sur-Arve, France

Investigational Site Number : 2500022

Juan-les-Pins, France

Investigational Site Number : 2500020

Le Chesnay, France

Investigational Site Number : 2500038

Libourne, France

Investigational Site Number : 2500033

Lyon, France

Investigational Site Number : 2500024

Marseille, France

Investigational Site Number : 2500002

Montpellier, France

Investigational Site Number : 2500047

Morlaix, France

Investigational Site Number : 2500040

Niort, France

Investigational Site Number : 2500026

Nîmes, France

Investigational Site Number : 2500017

Paris, France

Investigational Site Number : 2500001

Pessac, France

Investigational Site Number : 2500034

Pierre-Bénite, France

Investigational Site Number : 2500048

Saint-Pierre, France

Investigational Site Number : 2500028

Toulouse, France

Investigational Site Number : 2500029

Toulouse, France

Investigational Site Number : 2500010

Vantoux, France

Investigational Site Number : 2500035

Villeurbanne, France

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NCT07380711

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