RecruitingNCT07382986

IMPACT COPD Cohort (China)

Integrative Medicine Program for COPD With Comorbidity Management

Sponsor

Beijing Chao Yang Hospital

Enrollment

10,000 participants

Start Date

Feb 26, 2026

Study Type

OBSERVATIONAL

Conditions

Chronic Obstructive Pulmonary Disease (COPD)Multimorbidities

Summary

Chronic obstructive pulmonary disease (COPD) is a major chronic respiratory condition with high prevalence of multimorbidity. COPD and comorbidities interact dynamically, contributing to symptom fluctuation, acute exacerbations, hospitalization, and long-term disease progression. The IMPACT COPD Cohort (China) is a multicenter prospective observational cohort designed to establish a real-world evidence base for integrative Chinese-Western medicine management of COPD with comorbidities. The cohort integrates conventional clinical assessments (symptoms, questionnaires, spirometry, imaging, and biomarkers) with continuous multisensor digital monitoring (e.g., heart rate, blood pressure, activity, sleep patterns, and other physiological and behavioral measures) and digital Traditional Chinese Medicine (TCM) phenotyping (e.g., tongue, pulse, and facial diagnostics). The study aims to characterize risk profiles of high-risk populations and patients with confirmed comorbidities, develop and validate prediction models for comorbidity risk and acute exacerbation events, and support evidence generation for long-term management strategies with early screening and risk warning capabilities across hospital, community, and home settings.

Eligibility

Min Age: 40 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This is a large long-term study tracking patients with COPD (a chronic lung disease usually caused by smoking) in China, to better understand how the disease progresses over time. Researchers will collect detailed information about lung function, imaging, and quality of life to identify patterns and risk factors. **You may be eligible if...** - You are between 40 and 80 years old - You have been officially diagnosed with COPD according to current medical guidelines **You may NOT be eligible if...** - You had a COPD flare-up within the last 4 weeks - You have other serious lung diseases such as severe bronchiectasis, pneumoconiosis, or interstitial lung disease - You have cystic fibrosis - You need a permanent breathing machine through a tracheostomy - You have had a lung or organ transplant - You have lung cancer or another cancer that has spread widely - You have severe heart, liver, or kidney failure - You were hospitalized for a heart attack or heart failure in the last 3 months - You have had major chest, abdominal, or eye surgery in the last 3 months Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERReal-World Integrative COPD Care and Continuous Multisensor Monitoring

Participants will receive routine clinical care according to GOLD guideline and local clinical practice. This observational cohort collects longitudinal data through conventional clinical assessments (questionnaires, spirometry, imaging, and biomarkers) and continuous multisensor digital monitoring (e.g., heart rate, blood pressure, activity, and sleep), along with digital Traditional Chinese Medicine (TCM) phenotyping (tongue, pulse, and facial features). No study-mandated therapeutic intervention is assigned.