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RecruitingNot ApplicableNCT07383051

A Randomized Clinical Trial for Predictors of Successful Extubation of Pediatric Patients With or Without High Velocity Nasal Insufflation

Predictors of Successful Extubation of Pediatric Patients From Mechanical Ventilation With or Without Post Extubation High Velocity Nasal Insufflation

Sponsor

Cairo University

Enrollment

100 participants

Start Date

Sep 20, 2025

Study Type

INTERVENTIONAL

Conditions

High Velocity Nasal InsufflationSimple OxygenWeaning Criteria

Summary

A randomized clinical trial about predictors of successful extubation of pediatric patients from mechanical ventilation either on High Velocity Nasal Insufflation or simple nasal oxygen and comparing the outcome

Eligibility

Min Age: 2 MonthsMax Age: 13 Years

Inclusion Criteria3

  • Age between 2 months and 13 years old with minimum weight 4kg
  • Both sexes
  • Patients on mechanical ventilation for at least 24 hours for any indication

Exclusion Criteria3

  • Patients not ready for weaning from mechanical ventilation
  • Contraindications to use of High velocity nasal insufflation
  • Prolonged mechanical ventilation for more than 21 days
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Interventions

DEVICEComparing the outcome of pediatric patients after successful weaning on either High Velocity Nasal Insufflation or simple oxygen

A randomized clinical study is comparing between extubation on High Velocity Nasal Insufflation or simple nasal Oxygen ensuring that all patients had successful weaning predictors before extubation and comparing the outcome whether patient needed upgrading of oxygen support or re-intubation within 48 hours, presence of respiratory distress or stridor post extubation, time of complete weaning of oxygen support to room air and also morbidity and mortality.

DEVICEcomparing High Velocity Nasal Insufflation to simple oxygen after successful weaning of pediatric patients

A randomized clinical study is comparing between extubation on High Velocity Nasal Insufflation or simple nasal Oxygen ensuring that all patients had successful weaning predictors before extubation and comparing the outcome whether patient needed upgrading of oxygen support or re-intubation within 48 hours, presence of respiratory distress or stridor post extubation, time of complete weaning of oxygen support to room air and also morbidity and mortality.

Locations(1)

Cairo University

Cairo, Cairo Governorate, Egypt

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NCT07383051