RecruitingNot ApplicableNCT07386769

Interpersonal Brain Function in Opioid Use


Sponsor

University of California, San Diego

Enrollment

60 participants

Start Date

Feb 2, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to assess dyadic physiological coherence and subjective empathic attunement during meditation practices and their association with opioid-related outcomes.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Persons, aged 18 or older
  • Current near daily use of prescribed or illicit opioid agonists or mixed opioid agonist-antagonists for ≥90 days
  • Must be able to speak and understand English

Exclusion Criteria2

  • Cognitive Impairment that would preclude participation in the research protocol
  • Active suicidal intent or psychosis

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Interventions

BEHAVIORALMeditation

20 minutes of guided meditation during the laboratory session involving mindfulness of breathing and lovingkindness practice.

BEHAVIORALPsychoeducation

20 minute psychoeducational script on the impact of opioid use on the brain.


Locations(1)

University of California, San Diego

La Jolla, California, United States

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NCT07386769


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