RecruitingNCT07388108

Atrial Dyssynchrony to Predict Arrhythmias in the Postoperative Setting of Cardiovascular Surgery.

Atrial Electromechanical Alteration as a Predictor of Arrhythmias in the Postoperative Period After Cardiovascular Surgery


Sponsor

School of Medicine. National University of Cuyo

Enrollment

138 participants

Start Date

Feb 6, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

This study aims to improve the prediction for developing arrhythmias in the postoperative period of cardiovascular surgery by using non-invasive echocardiographic techniques that are sensitive to detect inter and intra-atrial dyssynchrony. The main question it aims to answer is: Do patients with atrial dyssynchrony are at increased risk of developing arrhythmias in the postoperative period of cardiovascular surgery? Patients admitted to the protocol will undergo an echocardiogram with atrial strain before surgery to determine the presence or absence of intra- and inter-atrial dyssynchrony and will be followed during hospitalization to assess the occurrence of atrial fibrillation in the postoperative period.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria2

  • Patients with criteria for non-mitral cardiovascular surgery, in sinus rhythm, and who gave informed consent to participate in the study.
  • Absence of atrial fibrillation upon hospital admission for surgery.

Exclusion Criteria5

  • Surgery of the mitral or tricuspid valve.
  • History of previous atrial fibrillation.
  • History of congenital heart disease or cardiac tumors.
  • Emergency surgery of the heart
  • Pour echocardiographic window

Interventions

DIAGNOSTIC_TESTAtrial dyssynchrony

To determine interatrial dyssynchrony, an adaptation of the echocardiographic atrial strain will be made so that both atria can be evaluated simultaneously. This new evaluation, OMEGA (ω) will yield the time to maximum deformation of the lateral segments of the right atrium and the lateral segments of the left atrium. Additionally, total atrial deformation will be evaluated via bi-atrial strain analysis. We will then measure the maximum deformation time-from P-wave onset to the maximum negative strain deflection-to assess its relationship with atrial contraction strain.


Locations(1)

Clínica de Cuyo

Mendoza, Mendozz, Argentina

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NCT07388108


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