Bowel Continence Across the Lifespan in People With Spina Bifida
Comparing Antegrade Versus Retrograde Enemas To Improve Bowel Continence Across the Lifespan in People With Spina Bifida
David Chu
943 participants
Apr 1, 2026
OBSERVATIONAL
Conditions
Summary
The goal of this observational study is to learn how different enema programs affect bowel control in children and adults with spina bifida. An enema program involves putting liquid into the large intestine (colon) to help someone poop. The main questions it aims to answer are: 1. How well do different enema programs prevent bowel accidents? 2. How do these enema programs affect independence, bowel symptoms, and quality of life? Researchers will compare two types of enema programs to see which works better and is easier for participants to manage. Participants starting a new enema program will answer online survey questions at 3 different timepoints over the course of 1 year.
Eligibility
Inclusion Criteria4
- Minimum age 5 years old
- Myelomeningocele diagnosis
- Starting a retrograde or antegrade enema program (or switching from one enema program to the other)
- English or Spanish speaking/literate
Exclusion Criteria1
- \- Other types of spinal dysraphism (e.g., lipomyelomeningocele, fatty filum)
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Interventions
A retrograde enema is a bowel management technique in which the enema is given through the rectum (end of the colon). This includes cone enemas, foley balloon enemas, and Transanal irrigation (e.g. Peristeen, Navina).
An antegrade enema is a bowel management technique in which an enema is given through a surgically-created tube that enters at the start of the colon. This includes MACES, cecostomy buttons, and Chait tubes.
Locations(24)
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NCT07390318