Dose De-escalation in Prostate Radiotherapy Using an MR-Linac in Two Fractions

This trial is testing whether a lower radiation dose — delivered very precisely using an MRI-guided radiation machine in just two sessions — is as safe and effective as standard radiotherapy for early-stage prostate cancer. The goal is to reduce radiation dose while targeting the tumor more accurately, potentially lowering side effects. **You may be eligible if...** - You are a man 18 or older with biopsy-confirmed prostate cancer - Your cancer is low to intermediate risk (Gleason score of 3+3, 3+4, or 4+3) - Your MRI shows a visible tumor area that can be targeted, with the tumor less than 2.5cm in size - Your MRI was performed within the past 3 months - You require radical (curative) radiotherapy **You may NOT be eligible if...** - Your cancer has spread beyond the prostate or is high-risk/very high-risk - You cannot have an MRI (e.g., certain metal implants) - You have previously had radiation therapy to the prostate area - You have significant pre-existing bowel or urinary problems Talk to your doctor to see if this trial is right for you.