RecruitingNot ApplicableNCT07397858

Cognition and Behavior With Sham Accelerated TMS

Studies of Cognition and Behavior Using Sham Accelerated Transcranial Magnetic Stimulation


Sponsor

University of California, Davis

Enrollment

25 participants

Start Date

Apr 11, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical study is to understand how a person's expectations about treatment can influence their mood, motivation, and reactions to everyday rewards. The study includes young people ages 15-25 who will complete a sham (placebo) version of an accelerated transcranial magnetic stimulation (TMS) treatment. No active brain stimulation is given. The main questions this study aims to answer are: 1. Do expectancy and treatment beliefs change during and after an accelerated sham TMS schedule? 2. Do these expectations influence mood, reward processing, or craving? 3. Does a more intensive schedule of sham sessions lead to different expectancy effects than a slower, once-daily schedule? Participants will: * Complete baseline clinical assessments and an MRI session * Undergo five days of accelerated sham TMS (no active brain stimulation is delivered) * Complete post-treatment MRI and follow-up assessments at 1 week and 4 weeks


Eligibility

Min Age: 15 YearsMax Age: 25 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called Transcranial Magnetic Stimulation Sham for people with depression. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICETranscranial Magnetic Stimulation Sham

All study participants will receive sham TMS (no active stimulation will be provided).


Locations(1)

UC Davis Medical Center

Sacramento, California, United States

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NCT07397858


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