RecruitingNot ApplicableNCT07399652

Artificial Intelligence-Guided Detection of Blood Vessels to Enhance Safety in Third-Space Endoscopic Procedures

Artificial Intelligence-Guided Detection of Anatomical Markers to Enhance Safety in Third-Space Endoscopic Procedures


Sponsor

Asian Institute of Gastroenterology, India

Enrollment

20 participants

Start Date

Feb 10, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This prospective study aims to evaluate the performance of a novel Artificial Intelligence (AI) clinical decision support tool during third space endoscopic procedures, such as Endoscopic Submucosal Dissection (ESD) and Peroral Endoscopic Myotomy (POEM). While these procedures are effective for treating gastrointestinal neoplasms and motility disorders, they carry risks of intraprocedural bleeding and perforation if submucosal blood vessels are not correctly identified and coagulated. Building on previous retrospective validation, this study will assess whether a real-time artificial intelligence model can assist endoscopists in detecting and delineating blood vessels more accurately and faster during live human procedures.


Eligibility

Plain Language Summary

Simplified for easier understanding

This study is testing whether AI-guided detection of blood vessels during advanced endoscopic procedures (called third-space endoscopy, where a doctor works inside the layers of the digestive tract wall) can improve safety by helping surgeons avoid accidentally cutting blood vessels. It focuses on patients with swallowing disorders or digestive tumors. **You may be eligible if...** - You have been diagnosed with achalasia (a swallowing disorder caused by the esophagus not relaxing properly) or a digestive tract tumor - You are scheduled for a third-space endoscopic procedure (such as POEM or STER) **You may NOT be eligible if...** - You have a condition that makes third-space endoscopy unsafe, such as a serious fungal infection (e.g., candidiasis) of the digestive tract - You have other medical conditions that your doctor determines make the procedure too risky Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEAI generated segmentation mask for sub-mucosal blood vessels

Real time AI generated segmentation mask or delineation contours for sub-mucosal blood vessels visible on the endoscopy monitor.


Locations(1)

Asian Institute of Gastroenterology

Hyderabad, Telangana, India

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NCT07399652


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