RecruitingPhase 2NCT07400952
Placebo-controlled Study to Evaluate the Safety and Efficacy of GLK-221 Ophthalmic Solution in Subjects With Keratoconus
Multicenter, Randomized, Double-Masked, Placebo-Controlled Study to Evaluate the Safety and Efficacy of GLK-221 Ophthalmic Solution in Subjects With Keratoconus
Sponsor
Glaukos Corporation
Enrollment
100 participants
Start Date
Dec 23, 2025
Study Type
INTERVENTIONAL
Conditions
Summary
Multi-center, parallel-group, placebo-controlled trial designed to assess the safety and efficacy of twice-daily topically administered GLK-221 Ophthalmic Solution in subjects with keratoconus.
Eligibility
Min Age: 18 YearsMax Age: 55 Years
Inclusion Criteria2
- Be ≥ 18 and ≤ 55 years of age
- Diagnosis of keratoconus in the study eye
Exclusion Criteria2
- Pregnant, lactating or planning a pregnancy
- Currently enrolled, or within 30 days prior to Screening were enrolled, in another investigational drug or device trial
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Interventions
DRUGGLK-221 Ophthalmic Solution
GLK-221 Ophthalmic Solution administered twice daily to both eyes
DRUGPlacebo Ophthalmic Solution
Placebo Ophthalmic Solution administered twice daily to both eyes
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07400952
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