RecruitingNCT07403188

A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101


Sponsor

Kyverna Therapeutics

Enrollment

70 participants

Start Date

Nov 24, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this long-term follow-up (LTFU) study is to collect delayed adverse events (AEs) and understand the persistence of KYV-101 (autologous CAR T cell product; gene-modified product), in participants who have been administered KYV-101 (gene-modified product; autologous CAR T cell product). This LTFU protocol will be open to any participant who received at least one infusion of KYV-101 in a previous Kyverna sponsored clinical trial or Investigator Initiated Trial (IIT).


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This is a long-term follow-up study designed to monitor the health and safety of people who previously received a CAR-T cell therapy called KYV-101 in an earlier clinical trial. CAR-T therapy reprograms your own immune cells to recognize and attack disease. Because this type of treatment can have long-lasting effects, this study tracks participants over an extended period to understand any lasting benefits or risks. **You may be eligible if...** - You received at least one infusion of KYV-101 as part of a previous KYV-101 treatment study - You are willing and able to provide informed consent to participate in this long-term follow-up program **You may NOT be eligible if...** - You did not previously participate in a KYV-101 parent treatment study - You are unable or unwilling to provide informed consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGKYV-101

Autologous fully-human anti-CD19 chimeric antigen receptor T-cell (CD19 CAR T) product.


Locations(1)

University of Colorado, Denver

Denver, Colorado, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07403188


Related Trials