RecruitingPhase 2NCT07404982

Reversal of Spinal Anesthesia Residual Motor Block Via Intrathecal Catheter

Reversal of Spinal Anesthesia Residual Motor Block Via Intrathecal Catheter: A Pilot Study


Sponsor

Beth Israel Deaconess Medical Center

Enrollment

20 participants

Start Date

Mar 19, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to determine the feasibility of administering a predetermined amount of normal saline into the intrathecal or subarachnoid space via a small spinal catheter to reduce or eliminate the effects of previously injected spinal anesthetic following lower extremity orthopedic surgery.


Eligibility

Inclusion Criteria2

  • Patients having elective lower extremity joint replacement surgery
  • Patients >18 years

Exclusion Criteria6

  • Contraindications to spinal anesthesia (refusal, lumbar spinal hardware, spinal abnormalities)
  • Patient on anticoagulation not withheld
  • Patient receiving re-operation on the same joint
  • Prior intra-cranial bleeding
  • Patient's ASA status >3
  • Non-English speaking

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Interventions

DRUGNormal Saline 10 mL Injection

Patients randomized to this arm will have saline administration via intrathecal catheter post-op prior to removal


Locations(1)

Beth Israel Deaconess Medical Center

Boston, Massachusetts, United States

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NCT07404982