RecruitingPhase 1NCT07405177

A Study of MK-7240 in Healthy Participants (MK-7240-009)

A Randomized, Open-label, Parallel-group Study to Assess the Pharmacokinetic Bioequivalence of Subcutaneously-administered Tulisokibart Delivered by 2 Different Autoinjectors in Healthy Participants


Sponsor

Merck Sharp & Dohme LLC

Enrollment

330 participants

Start Date

Mar 5, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this study is to learn what happens to MK-7240 in a healthy person's body over time (pharmacokinetic or PK study). Researchers also want to learn about the safety of MK-7240 and if people tolerate it.


Eligibility

Min Age: 18 YearsMax Age: 55 Years

Inclusion Criteria1

  • Has a body-mass index (BMI) between 18 and 32 kg/m\^2

Exclusion Criteria2

  • Has a history of more than 1 episode of herpes zoster infection or history of disseminated herpes zoster infection
  • Has a history of or current active tuberculosis (TB) infection or history of latent TB that was not fully treated

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Interventions

BIOLOGICALTulisokibart Form 1

Solution for injection.

BIOLOGICALTulisokibart Form 2

Solution for injection.


Locations(2)

Nucleus Network ( Site 0002)

Brisbane, Queensland, Australia

Nucleus Network ( Site 0001)

Melbourne, Victoria, Australia

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NCT07405177


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