RecruitingPhase 1Phase 2NCT07408232

A Phase 1/2 Study in Healthy Volunteers and Participants With Autosomal Dominant Retinitis Pigmentosa (RHO-adRP)

A Phase 1/2, First-in-Human Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of OCT-980 in Healthy Volunteers and Participants With Autosomal Dominant Retinitis Pigmentosa


Sponsor

Octant, Inc.

Enrollment

18 participants

Start Date

Mar 10, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

This integrated Ph1/2 clinical study is to assess the safety, tolerability and pharmacokinetics (PK), pharmacodynamics (PD) and efficacy of OCT-980 in healthy volunteers and participants with RHO-adRP.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Phase 1b/2: Cohort 1 - OCT-980 Tablet, a drug called Phase 1b/2: Cohort 2 - OCT-980 Tablet, and others for people with retinitis pigmentosa. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGPhase 1b/2: Cohort 1 - OCT-980 Tablet

OCT-980 tablets administered orally once daily at dose levels specified in the protocol

DRUGPhase 1b/2: Cohort 2 - OCT-980 Tablet

OCT-980 tablets administered orally once daily at dose levels specified in the protocol

DRUGPhase 1b/2: Cohort 3 - OCT-980 Tablet

OCT-980 tablets administered orally once daily at dose levels specified in the protocol

DRUGPhase 1b/2: Cohort 4 - OCT-980 Tablet

OCT-980 tablets administered orally once daily at dose levels specified in the protocol

DRUGPhase 1b/2: Cohort 5 - OCT-980 Tablet

OCT-980 tablets administered orally once daily at dose levels specified in the protocol


Locations(1)

Retina Foundation of the Southwest

Dallas, Texas, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07408232


Related Trials