RecruitingNot ApplicableNCT07409064

Effects of Exercise on Lipids and Endothelial Function in Youth

Effects of Exercise on Lipids and Endothelial Function in Youth With Obesity Participating in a Weight Loss Management Program


Sponsor

Children's Hospital Medical Center, Cincinnati

Enrollment

110 participants

Start Date

Sep 17, 2025

Study Type

INTERVENTIONAL

Summary

This study is for individuals who have a BMI that is at or above the 95th percentile and are participating in the Cincinnati Children's Hospital Healthworks! Structured weight loss program. The main reason for this research study is to determine how exercise affects an individual's high level of lipids (fats) in their blood and how well their blood vessels function.


Eligibility

Min Age: 10 YearsMax Age: 20 Years

Inclusion Criteria4

  • Age: 10-20 years
  • Obesity as defined by BMI ≥ 30 kg/m2 OR BMI ≥ 95%ile for age and sex
  • Planned to start the Healthworks! structured weight loss program.
  • English or Spanish speaking -

Exclusion Criteria2

  • \. Physician judgement about inability to finish the protocol
  • \-

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Interventions

OTHERExercise Program

Single arm study to evaluate the effectiveness of standard of care exercise program intervention. Effectiveness to be measured with a Garmin Vivosmart Fitness watch, endothelial function testing, carotenoid testing, and standard of care triglyceride level blood draw.


Locations(1)

Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, United States

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NCT07409064