RecruitingPhase 1NCT07413666

A Study of ORX489 in Healthy Adult Participants, Aged 18 to 60 Years

A Safety, Tolerability, Pharmacokinetic, Food Effect, and Proof-of-Concept Study of Single and Multiple Doses of ORX489 in Healthy Adults

Sponsor

Centessa Pharmaceuticals (UK) Limited

Enrollment

212 participants

Start Date

Feb 25, 2026

Study Type

INTERVENTIONAL

Conditions

Healthy Adult Male and Female Volunteers

Summary

Characterize the safety, tolerability and pharmacokinetics of ORX489 following single and multiple doses.

Eligibility

Min Age: 18 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called ORX489 Tablets and Placebo Tablets for people with healthy adult male and female volunteers. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 60 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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