Comparison of Skin Closure Techniques in Oncological Neurosurgical Procedures: Intradermal Running Suture Versus Transdermal Interrupted Sutures
Prospective Randomized Controlled Trial of Skin Closure Techniques in Oncological Cranial Neurosurgery: Interrupted Transdermal Sutures and Running Intradermal Suture.
Medical University of Warsaw
382 participants
Feb 1, 2026
INTERVENTIONAL
Conditions
Summary
The purpose of this study is to compare two commonly used methods of closing the skin after surgery for an intracranial tumor. Skin closure is one of the most important steps in neurosurgical procedures, as it has a major influence on how well the wound heals. In patients with brain tumors, proper wound healing is especially important because it may affect how soon additional treatments, such as radiotherapy or chemotherapy, can be started. There are different ways to close the skin after surgery, including running sutures and interrupted sutures. Both methods are widely used and considered safe. However, in oncological neurosurgery, there is limited scientific evidence comparing their effects, and the choice of technique is often based on the surgeon's personal experience. In this study, investigators will compare skin closure using running absorbable sutures with interrupted non-absorbable sutures. Investigators will evaluate how well, depending on used suturing methods, the wound heals and how often wound-related complications occur, such as infection, separation of the wound edges, or leakage of cerebrospinal fluid. Investigators believe that the results of this study will help improve wound care in patients undergoing neurosurgical treatment for brain tumors and, as a result, may contribute to better recovery and overall quality of life.
Eligibility
Inclusion Criteria2
- Male or female at least 18 years old
- Qualified for a craniotomy due to supratentorial intracranial tumor
Exclusion Criteria3
- Revision surgery due to recurrent brain tumor
- Emergency neurosurgical procedure
- Scalp incision involving glabrous skin (e.g. forehead) or facial regions (e.g. eyebrow)
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Interventions
Absorbable sutures used to perform continuous/running intradermal skin closure.
Non-absorbable sutures used to perform interrupted transdermal skin closure.
Locations(1)
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NCT07413796