RecruitingPhase 3NCT07418749

A Study of SHR-A2102 Versus Investigator's Choice of Chemotherapy in Patients With Platinum-based Chemotherapy and PD-(L)1 Inhibitor Treatment Failed Recurrent or Metastatic Cervical Cancer

An Open-label, Randomized, Controlled, Multicenter, Phase III Study of SHR-A2102 Versus Investigator's Choice of Chemotherapy in Patients With Platinum-based Chemotherapy and PD-(L)1 Inhibitor Treatment Failed Recurrent or Metastatic Cervical Cancer


Sponsor

Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Enrollment

398 participants

Start Date

Mar 30, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The main objective of this study is to evaluate the efficacy of SHR-A2102 versus investigator's choice of chemotherapy in patients with platinum-based chemotherapy and PD-(L)1 inhibitor treatment failed recurrent or metastatic cervical cancer.


Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Gemcitabine Hydrochloride for Injection, a drug called Paclitaxel for Injection (Albumin bound), and others for people with metastatic cervical cancer and recurrent cervical cancer. The study is currently recruiting participants at 1 location. People eligible for this study include women aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGSHR-A2102 for Injection

SHR-A2102 for injection.

DRUGPemetrexed Disodium for Injection

Pemetrexed Disodium for injection.

DRUGGemcitabine Hydrochloride for Injection

Gemcitabine Hydrochloride for injection.

DRUGTopotecan Hydrochloride for Injection

Topotecan Hydrochloride for injection.

DRUGPaclitaxel for Injection (Albumin bound)

Paclitaxel for injection (Albumin bound).


Locations(1)

Sun Yat-sen University Cancer Center

Guangzhou, Guangdong, China

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NCT07418749


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