RecruitingNCT07419347

Study of Glecaprevir/Pibrentasvir to Assess Safety Through Real-World Data

Retrospective Analysis of Glecaprevir/Pibrentasvir Safety and Concomitant Medications Through Integrated Real-World Data


Sponsor

AbbVie

Enrollment

2,000 participants

Start Date

Feb 27, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

The objective of this study is to assess the safety, tolerability and effectiveness of 8-week Glecaprevir/Pibrentasvir (G/P) in participants taking either prescribed or illicit drugs.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Prescribed 8 weeks of Glecaprevir/Pibrentasvir (G/P).
  • Treatment-naïve (for the current infection, participants that may have had prior infections which were resolved with treatment are considered naive for current infection as long as they have not received any treatment for the current infection.)
  • Is concomitantly on one or more prescription medications or illicit drugs.

Exclusion Criteria4

  • Treated with DAAs other than G/P.
  • History of decompensated cirrhosis.
  • Had Hepatitis-B virus (HBV) infection.
  • Had hepatocellular carcinoma (HCC).

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Locations(2)

Vancouver Infectious Diseases Centre /ID# 275313

Vancouver, British Columbia, Canada

St. Clair Medical Clinic /ID# 275334

Toronto, Ontario, Canada

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NCT07419347


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