RecruitingNot ApplicableNCT07419360

DRAIN: DRainage in Acute Decompensated Heart faIlure With Pleural effusioNs

Role of Therapeutic Thoracentesis in Hospitalized Patients With Acute Decompensated Heart Failure: Randomized Controlled Trial

Sponsor

Albany Medical College

Enrollment

216 participants

Start Date

Feb 15, 2026

Study Type

INTERVENTIONAL

Conditions

Congestive Heart Failure(CHF)Pleural Effusion Due to Congestive Heart Failure

Summary

The goal of this study is to assess if removal of fluid around the lungs (pleural effusion) by a routine procedure called as thoracentesis is helpful to decrease shortness of breath in hospitalized patients with congestive heart failure and have pleural effusion. Researchers will compare thoracentesis with medical therapy to medical therapy alone to see if one treatment is superior to the other treatment in relieving shortness of breath. Participants will : 1. Receive medical therapy with or without thoracentesis 2. Record degree of shortness of breath and quality of life before and after the intervention using predefined standard scales. 3. Telephonic call for 15- 30 mins at day 14 and 30 after enrollment to assess shortness of breath and quality of life

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether draining excess fluid from around the lungs (pleural effusion) helps patients hospitalized with acute decompensated heart failure — a sudden worsening of heart failure where fluid backs up into the lungs and body — recover faster and feel better. **You may be eligible if...** - You are over 18 years old - You have been diagnosed with acute decompensated heart failure - You have signs of fluid overload (such as leg swelling, fluid around the lungs, or fluid in the abdomen) - Your heart function has been assessed by echocardiogram **You may NOT be eligible if...** - You have very severe heart failure or other conditions that make drainage unsafe - You do not have measurable fluid accumulation Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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