Belgian Lung Function Study
Belgian Lung Function Study: Personalised Longitudinal Lung Function Analysis as a Marker of Disease Progression
KU Leuven
4,000 participants
Mar 25, 2026
OBSERVATIONAL
Conditions
Summary
Currently, it remains unclear how to manage serial lung function measurements in a clinical setting. The investigators aimed to tackle this problem by developing a machine learning (ML) model that can accurately predict population and individual lung function trajectories. These predictions would enable the investigators to identify positive or negative deviations, thereby revealing unexpected disease patterns. A prospective validation is needed that includes data on mortality, hospitalisations, emergency-room visits and patient-reported outcomes. Within this study, the goal is to validate the ML model with the data collected from this observational study.
Eligibility
Inclusion Criteria5
- Above 18 years old
- Diagnosed with a chronic respiratory disease and followed up in one of the participating Belgian hospitals
- Performed a complete lung function test (spirometry, body plethysmography and diffusion capacity) at baseline
- Have at least 3 historical spirometry measurements over a minimal time window of 2 years prior to inclusion
- Planned routine follow-up within standard clinical care in one of the participating hospitals
Exclusion Criteria2
- Patients who have had a lung transplantation
- Patients not being able to give consent to participate
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Locations(4)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07419555