Anesthesia Technique and Outcomes in Mechanical Thrombectomy for Acute Ischemic Stroke
Comparison of General Anesthesia and Sedoanalgesia on Mortality and Neurological Outcomes in Patients Undergoing Mechanical Thrombectomy for Acute Ischemic Stroke
Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
500 participants
Apr 1, 2026
OBSERVATIONAL
Conditions
Summary
This retrospective cohort study examined clinical outcomes in patients who underwent mechanical thrombectomy for acute ischemic stroke under general anesthesia or sedoanalgesia. Patient data from 2014 to 2018 were obtained from hospital medical records. Mortality and neurological outcomes were compared between anesthesia groups.
Eligibility
Inclusion Criteria4
- Age ≥18 years
- Acute ischemic stroke due to large vessel occlusion (MCA M1)
- Mechanical thrombectomy performed within 6 hours of symptom onset
- Pre-procedural TICI score 0-1
Exclusion Criteria6
- Age ≥100 years
- APACHE II score of 25 or higher
- Glasgow Coma Scale score below 10
- Requirement for endotracheal intubation before the procedure
- Patients discharged from the procedure to the intensive care unit while intubated
- Time from symptom onset to procedure exceeding 6 hours
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Interventions
Patients who underwent mechanical thrombectomy under general anesthesia, based on anesthesia records.
Patients who underwent mechanical thrombectomy under sedoanalgesia, based on anesthesia records.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07422649