Acute Ischemic Stroke Clinical Trials

154 recruitingLast updated: June 18, 2026

There are 154 actively recruiting acute ischemic stroke clinical trials across 37 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 4, Phase 1. Top locations include Beijing, Beijing Municipality, China, Beijing, China, Shanghai, China. Updated daily from ClinicalTrials.gov.


Acute Ischemic Stroke Trials at a Glance

154 actively recruiting trials for acute ischemic stroke are listed on ClinicalTrialsFinder across 6 cities in 37 countries. The largest study group is Not Applicable with 51 trials, with the heaviest enrollment activity in Beijing, Beijing, and Shanghai. Lead sponsors running acute ischemic stroke studies include Capital Medical University, Beijing Tiantan Hospital, and Xuanwu Hospital, Beijing.

Browse acute ischemic stroke trials by phase

Treatments under study

About Acute Ischemic Stroke Clinical Trials

Looking for clinical trials for Acute Ischemic Stroke? There are currently 143 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Acute Ischemic Stroke trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Acute Ischemic Stroke clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 154 trials

Recruiting
Phase 3

rhTNK-tPA for Acute Ischemic Stroke Under Simplified Imaging in the Extended Time Window

Acute Ischemic Stroke
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University750 enrolled1 locationNCT07606807
Recruiting
Phase 3

Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke

Acute Ischemic StrokeCerebral Stroke
Pharmazz, Inc.514 enrolled55 locationsNCT05691244
Recruiting
Not Applicable

Large Artery Occlusion Treated in Extended Time With Mechanical Thrombectomy Trial

Acute Ischemic Stroke
Fudan University336 enrolled1 locationNCT05326932
Recruiting
Phase 3

A Study to Test if Tenecteplase Helps People to Recover From an Acute Stroke When Given More Than 4.5 Hours After the Person Was Last Seen Well

Acute Ischemic Stroke
Boehringer Ingelheim1,325 enrolled242 locationsNCT07361302
Recruiting

Study to Collect Real-world Performance and Safety Data on Penumbra System® in Population With Acute Ischemic Stroke (AIS).

Acute Ischemic Stroke AIS
Penumbra Inc.200 enrolled10 locationsNCT07107022
Recruiting
Phase 2

Fructose for Acute Ischemic Stroke

Acute Ischemic Stroke
Ji Xunming,MD,PhD46 enrolled1 locationNCT07626541
Recruiting
Not Applicable

Efficacy and Safety of Tenecteplase Intravenous Thrombolysis in Acute Posterior Circulation Ischemic Stroke Within 4.5-24 Hours After Onset

Acute Ischemic Stroke
The First Affiliated Hospital of University of Science and Technology of China406 enrolled1 locationNCT07094763
Recruiting
Phase 1Phase 2

Human Placenta-derived 3D Mesenchymal Stem Cells(Guojianqingke)

Acute Ischemic Stroke
Chinese PLA General Hospital24 enrolled1 locationNCT07635758
Recruiting
Not Applicable

HBO After Thrombectomy for AIS With LVO

Acute Ischemic Stroke From Large Vessel Occlusion
Beijing Tiantan Hospital420 enrolled1 locationNCT07626450
Recruiting
Phase 2Phase 3

Minocycline After Successful Endovascular Thrombectomy Recanalization in Acute Anterior Circulation Large Vessel Occlusion (ATTRACTION-MINOA)

Acute Ischemic StrokeMinocyclineAnterior Circulation Brain Infarction+2 more
Xiang Luo860 enrolled1 locationNCT07594314
Recruiting
Not Applicable

Predictive Multimodal MRI Factors in Subacute Cerebral Artery Occlusiontreated by Thrombectomy (PIMISUTT)

Middle Cerebral Artery Acute Ischemic Stroke
Poitiers University Hospital50 enrolled1 locationNCT04651010
Recruiting
Phase 4

Safety and Efficacy of Adjunctive GM1 to Mechanical Thrombectomy for Acute Anterior Circulation Large Vessel Occlusion

StrokeAcute Ischemic Stroke
Xuanwu Hospital, Beijing868 enrolled1 locationNCT07519044
Recruiting
Phase 3

Emergent Large Vessel Occlusion Endovascular Rescue Therapy With Underlying Intracranial Stenosis

Acute Ischemic StrokeBrain StrokeStenting Treatment
ProMedica Health System342 enrolled1 locationNCT07356284
Recruiting
Phase 2Phase 3

Minocycline After Successful Endovascular Thrombectomy Recanalization in Posterior Circulation Arterial Occlusion (ATTRACTION-MINOP)

Acute Ischemic StrokeMinocyclineArterial Occlusion+2 more
Xiang Luo234 enrolled1 locationNCT07594301
Recruiting

Blood Pressure Variability and Ischemic Stroke Outcome

Blood Pressure VariabilityAcute Ischemic Stroke
Yale University150 enrolled3 locationsNCT05756257
Recruiting
Phase 1

Anisodine Hydrobromide for Patients With Acute Ischemic Stroke Undergoing Endovascular Therapy (HEAL)

Acute Ischemic Stroke
Capital Medical University92 enrolled2 locationsNCT07513233
Recruiting
Phase 3

Early Treatment of Atrial Fibrillation for Stroke Prevention Trial in Acute STROKE

Atrial FibrillationAcute Ischemic Stroke
Universitätsklinikum Hamburg-Eppendorf1,746 enrolled1 locationNCT05293080
Recruiting
Phase 2

Study of BB-031 in Acute Ischemic Stroke Patients (RAISE)

Acute Ischemic Stroke
Basking Biosciences, Inc.228 enrolled25 locationsNCT06226805
Recruiting
Phase 3

Precision Antiplatelet Therapy Guided by Platelet Aggregation Function in Patients With Acute Ischemic STROKE

Acute Ischemic StrokeClopidogrel Resistance
Sichuan Provincial People's Hospital5,138 enrolled1 locationNCT06853535
Recruiting
Phase 3

Efficacy and Safety of Interleukin-6 Receptor Inhibitor Combined With Endovascular Treatment in Patients With Acute Anterior Circulation Large Vessel Occlusion Stroke -2

Acute Ischemic Stroke
Capital Medical University692 enrolled53 locationsNCT07263776