Acute Ischemic Stroke Clinical Trials

130 recruiting

Acute Ischemic Stroke Trials at a Glance

138 actively recruiting trials for acute ischemic stroke are listed on ClinicalTrialsFinder across 6 cities in 38 countries. The largest study group is Not Applicable with 48 trials, with the heaviest enrollment activity in Beijing, Beijing, and Shanghai. Lead sponsors running acute ischemic stroke studies include Capital Medical University, Beijing Tiantan Hospital, and Xuanwu Hospital, Beijing.

Browse acute ischemic stroke trials by phase

Treatments under study

About Acute Ischemic Stroke Clinical Trials

Looking for clinical trials for Acute Ischemic Stroke? There are currently 130 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Acute Ischemic Stroke trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Acute Ischemic Stroke clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 138 trials

Recruiting
Phase 2

Efficacy and Safety of LT3001 on Treating the Acute Ischemic Stroke

Acute Ischemic Stroke
Shanghai Pharmaceuticals Holding Co., Ltd300 enrolled28 locationsNCT05686642
Recruiting
Not Applicable

Radial Versus Femoral Access For Thrombectomy in Patients With Acute Basilar Artery Occlusion

Acute Ischemic Stroke
Jinling Hospital, China386 enrolled1 locationNCT05903560
Recruiting
Phase 3

A Study to Test if Tenecteplase Helps People to Recover From an Acute Stroke When Given More Than 4.5 Hours After the Person Was Last Seen Well

Acute Ischemic Stroke
Boehringer Ingelheim1,325 enrolled224 locationsNCT07361302
Recruiting
Phase 2

Transcranial Direct Current Stimulation for Treatment of Acute Ischemic Stroke

Acute Ischemic Stroke
University of California, Los Angeles120 enrolled3 locationsNCT06440707
Recruiting
Not Applicable

Endovascular Therapy Versus Best Medical Treatment for Acute Large Vessel Occlusion Stroke With Low NIHSS

Mild Neurocognitive DisorderThrombectomyAcute Ischemic Stroke
First Affiliated Hospital of Wannan Medical College264 enrolled1 locationNCT06143488
Recruiting
Phase 4

Low-Dose Tenecteplase for Acute Ischemic Stroke Treatment in Aging Patients

Acute Ischemic Stroke Patients
Southwest Hospital, China798 enrolled49 locationsNCT07294209
Recruiting

Efficacy and Safety of PCSK9 Inhibitors in Patients With Large-Artery Atherosclerosis (LAA) Ischemic Stroke

Acute Ischemic Stroke
First Affiliated Hospital of Harbin Medical University1,000 enrolled1 locationNCT07540741
Recruiting
Phase 2

A Study of TAK-755 in Adults With Acute Ischemic Stroke

Acute Ischemic Stroke
Takeda222 enrolled1 locationNCT07392450
Recruiting
Phase 3

OPtimizing REperfusion by Intra-Arterial ThRomboLysis as Adjunct to Endovascular Treatment for Medium Vessel Occlusion

Acute Ischemic Stroke
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University530 enrolled1 locationNCT07137832
Recruiting

EmboTrap ® II Revascularization Device (Neuravi) in Acute Ischemic Stroke

Acute Ischemic Stroke
Niguarda Hospital100 enrolled1 locationNCT03601702
Recruiting
Phase 3

Albumin for Patients With Acute Large Vessel Occlusive Stroke Undergoing Endovascular Therapy -2

Acute Ischemic Stroke
Capital Medical University1,192 enrolled12 locationsNCT07263308
Recruiting
Not Applicable

Non-invasive Vagus Nerve Stimulation to Reduce Inflammation and Brain Injury Blood Biomarkers Following an Acute Ischemic Stroke

Acute Ischemic StrokeLarge Vessel Occlusion
Washington University School of Medicine65 enrolled1 locationNCT07404852
Recruiting

Anesthesia Technique and Outcomes in Mechanical Thrombectomy for Acute Ischemic Stroke

Acute Ischemic Stroke
Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital500 enrolled1 locationNCT07422649
Recruiting
Not Applicable

Medical Management With Endovascular Thrombectomy Versus Medical Management Alone in Patients Presenting Beyond 24 Hours of Last Known Well

Acute Ischemic Stroke
Amrou Sarraj408 enrolled6 locationsNCT07115940
Recruiting
Not Applicable

NeVa ONE Registry Study

Acute Ischemic Stroke
Vesalio600 enrolled3 locationsNCT04562194
Recruiting
Not Applicable

General Versus Regional Anesthesia for Carotid Endarterectomy at Acute Ischemic Stroke Trial

Acute Ischemic Stroke
Pirogov Russian National Research Medical University100 enrolled1 locationNCT06175715
Recruiting
Not Applicable

Safety and Efficacy Evaluation of the Ceretrieve Device in the Treatment of AIS Patients

Acute Ischemic Stroke
Ceretrieve Ltd.132 enrolled1 locationNCT06733246
Recruiting
Phase 3

Tenecteplase Before Interhospital Transfer for EVT in Acute Anterior Circulation LVO at 4.5-24 Hours

Acute Ischemic StrokeLarge Vessel OcclusionTransportation of Patients
Xuanwu Hospital, Beijing572 enrolled2 locationsNCT07253181
Recruiting
Phase 2

Study of BB-031 in Acute Ischemic Stroke Patients (RAISE)

Acute Ischemic Stroke
Basking Biosciences, Inc.228 enrolled24 locationsNCT06226805
Recruiting
Phase 4

Tenecteplase Before Interhospital Transfer in Acute Basilar Artery Occlusion at 4.5 to 24 Hours

Acute Ischemic StrokeBasilar Artery Occlusion
Xuanwu Hospital, Beijing316 enrolled1 locationNCT07203625