RecruitingNot ApplicableNCT07423767

Effects of a Preoperative Cognitive-Behavioral Intervention on Kinesiophobia and Function in Anterior Cruciate Ligament Reconstruction

Sponsor

Peking University Third Hospital

Enrollment

44 participants

Start Date

Feb 14, 2026

Study Type

INTERVENTIONAL

Conditions

Anterior Cruciate Ligament (ACL) Tear

Summary

This study aims to systematically elucidate the integrative effects of psychological rehabilitation on the "brain-psychology-motor" triad in patients with anterior cruciate ligament (ACL) rupture. We plan to recruit 44 patients (aged 18-45) diagnosed with ACL rupture and scheduled for reconstruction surgery at Peking University Third Hospital, who will be randomly assigned to two groups. Through synchronous acquisition of questionnaire scores, motor performance data (gait, jogging, postural stability), and central neural activity (EEG), this research seeks to establish a foundation for developing neuroscience evidence-based, precision rehabilitation strategies.

Eligibility

Min Age: 18 YearsMax Age: 45 Years

Inclusion Criteria5

Patients aged 18 to 45 years with a diagnosis of anterior cruciate ligament (ACL) rupture.
ACL rupture within 3 months prior to enrollment.
First-time ACL rupture with a scheduled reconstruction surgery at this institution.
The affected knee shows no significant redness, swelling, pain, or inflammation, with basic activities of daily living restored.
No injury or only mild (grade I) injury to the posterior cruciate ligament, medial collateral ligament, or lateral collateral ligament.

Exclusion Criteria9

Body mass index (BMI) less than 18.5 or greater than 35 kg/m².
Age older than 45 years or younger than 18 years.
ACL rupture with a duration exceeding 3 months.
Concurrent severe injury (greater than grade I sprain) to the posterior cruciate ligament, medial collateral ligament, or lateral collateral ligament. (Note: Grade II indicates partial tear with ligament thickening, laxity, and partial fiber disruption; Grade III indicates complete rupture).
Concurrent severe meniscal tear.
History of prior knee surgery (e.g., meniscal repair, ligament reconstruction, joint replacement, arthroscopic debridement).
Presence of other significant knee pathologies, such as: knee osteoarthritis, knee tumor, rheumatoid arthritis, tuberculosis, or active infectious/inflammatory diseases of the knee.
Concurrent fracture, dislocation, or other osseous injuries involving the knee.
Unwillingness to receive the treatment protocol of this study.

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Interventions

OTHERCognitive-Behavioral Intervention

This is a preoperative psychological intervention that uniquely combines a single in-person session (featuring guided practice of normal movement without assistive devices) with weekly phone support for 3-4 weeks, specifically designed to reduce kinesiophobia before anterior cruciate ligament reconstruction surgery.

OTHERControl group

This group receives standard preoperative care only (no psychological intervention). They undergo identical outcome assessments at the same time points as the intervention group.