ClinicalTrialsFinder
RecruitingNot ApplicableNCT07425249

Impact of Chewing Gum on Postoperative Gut Motility in Gastrointestinal Surgery Patients

Impact of Chewing Gum on Postoperative Gut Motility in Gastrointestinal Surgery Patients: A Randomized Controlled Trial at Khyber Teaching Hospital, Peshawar, Pakistan

Sponsor

Khyber Medical University Peshawar

Enrollment

96 participants

Start Date

Jan 1, 2026

Study Type

INTERVENTIONAL

Conditions

Postoperative IleusDelayed Gastrointestinal MotilityPostoperative Gut Dysfunction

Summary

Postoperative ileus (POI) is a frequent complication after abdominal surgery, leading to delayed gastrointestinal motility, prolonged hospital stay, and increased patient discomfort. Chewing gum, as a form of sham feeding, has been proposed to stimulate gut motility through vagal stimulation and increased gastrointestinal secretions. This randomized controlled trial aims to assess the effect of chewing gum on early recovery of gastrointestinal motility in patients undergoing open gastrointestinal surgery.

Eligibility

Min Age: 17 YearsMax Age: 85 Years

Inclusion Criteria4

  • Age between 17 and 85 years.
  • Patients of either gender.
  • Undergoing open gastrointestinal surgical procedures (elective or emergency).
  • Willing to participate and able to provide informed consent.

Exclusion Criteria6

  • Patients with metabolic or endocrine disorders (diabetes mellitus, hypothyroidism, or hyperthyroidism).
  • Patients with renal disease or electrolyte imbalance.
  • Patients with chronic constipation or neuromuscular disorders.
  • Patients with substance abuse or drug addiction.
  • Patients receiving medications affecting gut motility (calcium channel blockers or antiepileptic drugs).
  • Patients with dental prosthesis or undergoing laparoscopic gastrointestinal surgery.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

BEHAVIORALChewing Gum

Participants will chew glucose/carbohydrate-containing chewing gum for 15 minutes, three times daily, starting 6 hours after surgery and continuing for 48 hours or until the first passage of flatus or stool, in addition to standard postoperative care.

Locations(1)

Khyber Teaching Hospital

Peshawar, KPK, Pakistan

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07425249

Related Trials

Restrictive vs Liberal Intraoperative Fluid Strategy and Postoperative Outcomes After Elective Cesarean Section

NCT074406671 location

Use of Beetroot Juice to Protect Against Postoperative Ileus Following Colorectal Surgery: BEET IT Study

NCT051330246 locations

Pyridostigmine Efficacy and Safety for Treatment of Ileus After Colorectal Surgery

NCT053344851 location

Low Pressure Pneumoperitoneum and Postoperative Ileus

NCT053444172 locations

Simple Bed Exercises for Reducing Postoperative Ileus in Colorectal Surgical Patients.

NCT070140461 location