Adapting RDAD for DS
Adapting the RDAD Intervention for Individuals With Down Syndrome Phase 3- Pilot Test
University of Kansas Medical Center
40 participants
Mar 31, 2026
INTERVENTIONAL
Conditions
Summary
The goal of this clinical trial is to observe feasibility and initial efficacy of a remotely delivered exercise and dementia caregiving intervention in older adults with Down syndrome and their caregivers.
Eligibility
Inclusion Criteria8
- Age >35 yrs. with a diagnosis of DS as self-reported or reported by caregiver. This age range was selected as cognitive decline related to AD is observed at age ~31 in adults with DS.
- Sufficient functional ability to understand directions, communicate preferences, wants, and needs through spoken language.
- Living at home or in a supported living environment with a parent/caregiver who agrees to serve as a study partner.
- Self-reported ability to participate in physical activity.
- Age ≥18 yrs.
- Reports being a primary caregiver of an adult with DS.
- English speaking.
- Self-reported ability to participate in physical activity.
Exclusion Criteria4
- Unable to participate in moderate-to-vigorous physical activity.
- Self-reported, cardiovascular, metabolic or renal disease and/or signs or symptoms.
- Unable to participate in moderate PA, i.e., brisk walking.
- Self-reported, cardiovascular, metabolic or renal disease and/or signs or symptoms.
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Interventions
Participants will take part in thrice weekly exercise sessions using pre-recorded videos designed for older adults with Down syndrome. Participants will join video call and follow along with the video. A staff member familiar with the population will be on the call to provide modifications, encouragement and ensure participant safety.
Caregivers will join a once-weekly education session held via video call and led by a trained staff member. Education content will include how to support and manage challenging behaviors of older adults with Down syndrome who may be experiencing Alzheimer's disease-related symptoms.
Locations(1)
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NCT07425769