RecruitingNCT07427160
Prognostic Role of Macular Neovascular Membrane Subtype in Pneumatic Displacement of Macular Hemorrhages
Sponsor
Marco Mazzola
Enrollment
60 participants
Start Date
Oct 15, 2025
Study Type
OBSERVATIONAL
Conditions
Summary
This study investigates the prognostic value of macular neovascularization (MNV) subtypes in patients treated with pneumatic displacement for submacular hemorrhage. The researchers will compare anatomical and functional outcomes (visual acuity) between PCV, RAP, and other MNV forms within a Caucasian cohort to identify subtype-specific predictors of recovery.
Eligibility
Min Age: 50 Years
Inclusion Criteria6
- Patients undergoing pneumatic displacement (PD) for submacular hemorrhage (SMH), secondary to macular neovascularization (MNV)
- Age 50 years or older at the time of SMH diagnosis
- Caucasian ethnicity
- SMH involving the central or internal ring of the Early Treatment Diabetic Retinopathy Study (ETDRS) grid (within a 3 mm circumference centered on the fovea)
- SMH dimensions equal to or greater than one papillary diameter
- Pneumatic displacement treatment performed within 36 hours of SMH diagnosis
Exclusion Criteria8
- SMH estimated to be present for more than 15 days at the time of diagnosis
- SMH secondary to conditions other than MNV
- Presence of proliferative diabetic retinopathy in the study eye
- Aphakia in the study eye
- Inadequate pupillary dilation, media opacities, or other impediments to retinal imaging
- Previous pneumatic displacement procedures for SMH in the study eye
- Ocular surgery in the 8 weeks preceding the pneumatic displacement intervention
- Follow-up duration of less than 6 months following the procedure
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Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07427160