Exploration of Circulating microRNAs as Biomarkers of Chemo-induced Peripheral Neuropathy: a Study in Cancer Patients

This study is investigating whether small molecules in the blood called microRNAs could serve as early warning signs for nerve damage (peripheral neuropathy) caused by certain chemotherapy drugs. Nerve damage is a common and sometimes permanent side effect of these treatments. **You may be eligible if...** - You are being treated for colorectal cancer and are scheduled to receive oxaliplatin-based chemotherapy for at least 6 cycles, OR - You are being treated for lung cancer and are scheduled to receive paclitaxel-based chemotherapy for at least 4 cycles **You may NOT be eligible if...** - You have a neurodegenerative disease such as Parkinson's or Alzheimer's - You have had a stroke - You already have nerve damage or neuropathy before starting chemotherapy - You have significant pain (pain score 4/10 or higher) - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.